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Hemorrhagic vasculitis in Child SlideShare

VASCULITIS IN CHILDREN Classification Overlap of signs & symptoms Etiology is unknown One etiology maybe associated with different vasculitidies. e.g. Hepatitis B was reported with - Cutaneous vasculitis Igower 1978) - Cryoglobulinaemia vasculitis (Levo 1977) - Glomerulonephritis (Combas 1971) - Polyarteritis (Gocke 1970) Size of blood. Kawasaki's Vasculitis• MucoCutaneous Lymph node syndrome• Children < 5 years of age mostly• Desquamative erythematous rashes involvingthe skin, mucus membranes, cervicallymphadenopathy• 25 % develop coronary artery aneurysms inthe convalescent stage of the illness 29 Common Features Macules Cryoglobulinemic vasculitis. Acute hemorrhagic edema of enfancy Shaimaa Elkoly, M.D. Cairo University 18. Common Features Hemorrhagic bullae (vesicles) : Small vessel involvement throughout the dermis can result in necrosis of overlying tissue and extravasation of red blood cells Hemorrhagic syndromes Physical aspects Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website The course of hemorrhagic vasculitis is cyclical: a clearly delineated debut 1-3 weeks after acute viral or bacterial infection, vaccination and other causes and recovery in 4-8 weeks. Single observations of hemorrhagic vasculitis in children, which proceeds extremely hard in the form of fulminant purpura, are described

Pediatric vasculitis dr inayat ullah - SlideShar

1. Sov Zdravookhr Kirg. 1971 Nov-Dec;6:17-22. [The clinical characteristics of hemorrhagic vasculitis in children]. [Article in Russian] Il'in AA IgA Vasculitis. IgA vasculitis (Henoch-Schönlein purpura syndrome) is an IgA immunocomplex disease characterized by the involvement of multiple organs, including the gastrointestinal tract, skin, synovial membranes, and kidneys. It is the most common vasculitis in children between 4 and 7 years of age CASE REPORT Open Access Acute multifocal hemorrhagic retinal vasculitis in a child: a case report Malik Y. Ghannam1*, Mohammed Naseemuddin2, Peter Weiser2,3 and John O. Mason III2 Abstract Background: Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidenc

Hemorrhagic vasculitis (synonyms disease - rheumatic/allergic purpura (ICD 10), kapilliarotoxicos) is an infectious-allergic disease. It is associated with damage to small blood vessels of the body. This breaks their structure and there is avascular (not associated with infection) inflammation of their walls. This affects the small blood vessels located in the skin and internal organs 1. Pediatriia. 1971 Aug;50(8):58-65. [Hemorrhagic vasculitis (Schönlein-Henoch disease) in children]. [Article in Russian] Matveev MP. PMID Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence. It was first reported by Blumenkranz et al. in 1988 as an episodic disease that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult. In children, hemorrhagic vasculitis is often caused by hypothermia or a serious viral disease. The disease is more often characterized by fulminant course. In this disease, children more often than adults have systolic heart murmurs of a functional nature. In boys with hemorrhagic vasculitis, bilateral testicular lesions are observed in some cases 1. Probl Gematol Pereliv Krovi. 1960 Apr;5:45-7. [Blood picture in hemorrhagic vasculitis (Schoenlein-Henoch disease) in children]. [Article in Russian

Vasculitis - SlideShar

Leukocytoclastic vasculitis presenting as acute hemorrhagic edema in a 21-year-old patient. Int J Dermatol. vol. 50. 2011. pp. 860-2. (A case report of a 21 year old woman with acute hemorrhagic edema suggests that this disorder may occur in adults, and perhaps goes unretcognized by those not familar with the entity. Acute hemorrhagic edema of infancy (AHEI) is an unusual form of leukocytoclastic vasculitis that affects children younger than 2 years and frequently is preceded by drug intake, vaccination, or a variety of infections. It is characterized by an abrupt onset of fever, purpuric lesions, and peripheral Vasculitis is a group of disorders that destroy blood vessels by inflammation. Both arteries and veins are affected. Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. Vasculitis is primarily caused by leukocyte migration and resultant damage. Although both occur in vasculitis, inflammation of veins or arteries on their own are separate entities

Cutaneous vasculitis - SlideShar

HSP is a small-vessel vasculitis that typically affects children. About half of patients will report a preceding upper respiratory illness and present with low-grade fever and malaise. Common symptoms of HSP are arthralgias localized to the ankles and knees, abdominal pain with hematochezia, hematuria, scrotal edema, headaches, and rash Acute hemorrhagic edema of infancy (AHEI), also known as postinfectious cockade purpura, Seildlmayer's disease and Finkelstein's disease, is an acute cutaneous leukocytoclastic vasculitis first described in the United States in 1913 by Snow [ 1, 2 ]. It is a disease that affects children between 4 and 24 months of age and is characterized by a.

Hemorrhagic Syndromes - SlideShar

Hemorrhagic vasculitis in children Symptoms and

The occurrence of hemorrhagic bullae in children with HSP is rarely encountered. This report describes a 4.5-year-old female patient with HSP associated with hemorrhagic bullous lesions. Henoch-Schönlein purpura (HSP) is a vasculitis of small-sized blood vessels, resulting from immunoglobulin-A-mediated inflammation Although more commonly seen in children, IgA vasculitis can occur in adults and presentations are often severe1,2. A 67-year-old woman with a history of chronic sinusitis, asthma, and allergic rhinitis presented with 4 months of painful, ulcerating skin lesions on her lower extremities, arthralgia, and stocking and glove paresthesia. She denied upper respiratory, gastrointestinal, urinary. CASE REPORT Open Access Acute multifocal hemorrhagic retinal vasculitis in a child: a case report Malik Y. Ghannam 1*, Mohammed Naseemuddin 2, Peter Weiser2,3 and John O. Mason III 2 Abstract. Complications of vasculitis include: Organ damage. Some types of vasculitis can be severe, causing damage to major organs. Blood clots and aneurysms. A blood clot may form in a blood vessel, obstructing blood flow. Rarely, vasculitis will cause a blood vessel to weaken and bulge, forming an aneurysm (AN-yoo-riz-um). Vision loss or blindness

[Hemorrhagic vasculitis in children]

  1. Acute hemorrhagic edema (AHE) is a unique vasculitis of young children aged 4-24 months. There is sudden onset of fever with marked tender, symmetric edema and large, expanding purpura of the hands, feet, and face (Figures 6-16 and 6-17). Centrifugal spread leads to large targetoid purpura, quite distinct from the smaller palpable purpura of HSP
  2. al.
  3. HEMORRHAGIC STROKE: LOCATIONS 6 INTRACEREBRALHEMORRHAGE MOST COMMON CAUSE : BLOOD VESSEL WALL DAMAGE DUE TO HYPERTENSION-60% OF CASES OTHER CAUSES: • Autoregulatory dysfunction (re-perfusion injury, hemorrhagic transformation) • Arteriopathy (amyloid angiopathy, moya-moya) • Altered hemostasis (thrombolysis, anticoagulation
  4. Acute haemorrhagic oedema (hemorrhagic edema with the American spelling) is a rare type of cutaneous small vessel vasculitis with a characteristic presentation in infants. It consists of a clinical triad of: Acute haemorrhagic oedema of infancy was originally described by Snow in the USA in 1913
  5. We reported the case of a two-old-year boy with a painful acute hemorrhagic edema. This is a self-limited benign condition: usually, affected children are well appearing and this strongly support the diagnosis. In the opposite, in our case, we observed a painful presentation of the edema. Therefore, we demonstrated that rarely, this condition could have also a painful presentation
  6. [Hemorrhagic vasculitis in children.] USONYTE J. Sveikatos Apsauga, 01 Dec 1962, 7: 3-8 Language: lit PMID: 13995543 . Share this article Share with email Share with twitter Share with linkedin Share with facebook. Abstract . No abstract provided. Similar Articles . To arrive at the top five similar articles we use a word-weighted algorithm to.
  7. Arterial ischemic stroke is the most common type of childhood stroke. AIS occurs when an artery is blocked by a blood clot. Arteries are the blood vessels that carry blood to the brain. Two pairs of arteries carry blood in the neck.The first pair are located at the front of the neck. They are called the c arotid arteries. The second pair are located at the back of the neck

Business case study report format the turning point of my life a.j. cronin essay vasculitis child case in Hemorrhagic study. Essays topics for 6th grade ap lit essay questions 2019 , research paper word format video essays on youtube case Hemorrhagic vasculitis study child inUva college of arts and sciences essay prompt corruption in everyday. Acute hemorrhagic edema of infancy is an uncommon benign cutaneous vasculitis. Despite its worrisome presentation, it carries good prognosis with rarely reported systemic involvement. Management of these cases has been an area of debate with majority of physicians adopting conservative modalities. We report a case that presented with classic triad of rash, low grade fever, and peripheral edema.

Von Willebrand disease is a genetic condition that causes: (thrombotic, hemorrhagic) condition. thrombosis. hemorrhage. anemia. infection. 1 points . Question 2 ; The development of Kawasaki disease in young children is caused by: vasculitis of unknown cause (ANSWER Vascular bleeding disorders result from defects in blood vessels, typically causing petechiae, purpura, and bruising but, except for hereditary hemorrhagic telangiectasia, seldom leading to serious blood loss.Bleeding may result from deficiencies of vascular and perivascular collagen in Ehlers-Danlos syndrome and in other rare hereditary connective tissue disorders (eg, pseudoxanthoma. Cerebral vasculitis related to toxins - Cocaine, amphetamines, heroin, LSD and glue sniffing inflame the cerebral blood vessels. Cerebral vasculitis related to neoplasms - Diseases of the arteries may rarely complicate systemic tumors. Meningitis caused by cancer or lymphoma may affect the small and middle-sized intracranial arteries Hereditary hemorrhagic telangiectasia (tuh-lan-jee-uk-TAY-zhuh) is an inherited disorder that causes abnormal connections, called arteriovenous malformations (AVMs), to develop between arteries and veins. The most common locations affected are the nose, lungs, brain and liver. These AVMs may enlarge over time and can bleed or rupture, sometimes. Wells LC et Al, Arch Dis Child 200125 p220 22 Performance of Lab Test Wells LC et Al, Arch Dis Child 200125 p220 23 Coagulation Profiles Willword, Pediatric Emergency Care, 2003 Vol 19(4) p. 244 24 The Management of fever and petechiaemaking sense of rash decisionsBrogan PA,Raffles A. Arch Dis Child 200083506-

Hemorrhagic Vasculitis in Children: Causes, Symptoms and

Hemorrhagic vasculitis in children and adults what is it

Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine.. Vasculitides are a heterogeneous group of autoimmune diseases, all characterized by inflammation of blood vessels (vasculitis) and subsequent ischemia and damage to the organs supplied by these vessels. Vasculitis may occur as a primary disease or as a secondary response to an underlying disease (e.g., hepatitis B infection) ?Note: This page may contain content that is offensive or inappropriate for some readers. purpura [per´pu-rah] a hemorrhagic disease characterized by extravasation of blood into the tissues, under the skin, and through the mucous membranes, and producing spontaneous bruises, ecchymoses, and petechiae (small hemorrhagic spots) on the skin. (See plate in. Neonatal acute hemorrhagic edema of childhood: case report and review of the English-language literature. Pediatr Dermatol. 1996 Jan-Feb. 13(1):39-44. . Allen DM, Diamond LK, Howell DA. Anaphylactoid purpura in children (Schonlein-Henoch syndrome): review with a follow-up of the renal complications. AMA J Dis Child. 1960 Jun. 99:833-54 Summary: We report a patient with acute hemorrhagic leukoencephalitis with a focus on serial MR imaging findings. Initial MR imaging of a 42-year-old woman revealed a 2.5-cm focal nonhemorrhagic lesion in the left thalamus and internal capsule. Twenty-four days later, fever and altered consciousness developed, and MR imaging showed huge masslike lesions in both frontal lobes, mainly involving.

Hemorrhagic vasculitis in adults and children - causes

Rarely, hemorrhagic bullae, ulcerations or dermal scarring may be seen. On histopathology (Figures 4 and 5) leukocytoclastic vasculitis, characterized by neutrophilic infiltration and prominent nuclear fragmentation, involving the upper and middle layers of the dermis with IgA deposition on immunofluorescence, is seen. Angioedema (nonpitting. Chicago—November 5, 2011 In patients with a devastating form of vasculitis who are in remission, stress can be associated with a greater likelihood of the disease flaring, according to a new study by investigators at Hospital for Special Surgery (HSS).. This is the first study to suggest that mental health is a risk factor in patients with vasculitis, a group of autoimmune disorders. Acute hemorrhagic edema of infancy is a rare leukocytoclastic vasculitis that affects infants and children aged 4 to 24 months. We report a case of a 5-month-old girl with purpuric lesions with associated hemorrhagic lacrimation and epistaxis Lacunar infarcts are small infarcts in the deeper parts of the brain (basal ganglia, thalamus, white matter) and in the brain stem. They are responsible for about 20 percent of all strokes. They are caused by occlusion of deep penetrating branches of major cerebral arteries and are particularly common in hypertension and diabetes, which are associated with severe atherosclerosis of small. AHOI is a rare cutaneous small vessel vasculitis.1 Considered a mild variant of Henoch-Schonlein purpura,2 the aetiology is thought to be immune complex-mediated, reported following infections, medications and immunisation. It consists of a clinical triad of large bruise-like lesions, oedema and fever. The bruising develops over 24-48 hours, often having a targetoid or cockade appearance

Viral hemorrhagic fever (VHF) refers to a diverse group of viral pathogens that are characterized clinically by fever and a bleeding diathesis. Manifestations may include flushing of the face and chest, petechiae, mucosal and gastrointestinal bleeding, frank bleeding, malaise, edema, hypotension, myalgias, headache, vomiting, and diarrhea Although more commonly seen in children, IgA vasculitis can . occur in adults and presentations are often severe. 1,2. year-old woman with a history of chronic sinusitis, A 67-asthma, and allergic rhinitis presented with 4 months of pain-ful, ulcerating skin lesions on her lower extremities, arthralgia, and stocking and glove paresthesia Acute Multifocal Hemorrhagic Retinal Vasculitis (AMHRV) is a rare disease with unknown incidence that presents with abrupt onset of visual loss associated with retinal vasculitis, retinal hemorrhage, non-confluent posterior retinal infiltrates, vitreous cellular inflammation and papillitis in, otherwise, healthy adult individuals [Certain criteria of the activity of hemorrhagic vasculitis in children] Il'in AA. Voprosy Okhrany Materinstva i Detstva, 01 Apr 1976, 21(4): 30-33 Language: rus PMID: 997340 . Share this article Share with email Share with twitter Share with linkedin Share with facebook. Abstract . No abstract provided..

Acute hemorrhagic encephalomyelitis (AHEM), also known as acute hemorrhagic leukoencephalitis (AHLE), Hurst disease or Weston Hurst syndrome, is a very rare form of demyelinating disease.It occurs sporadically and may be considered as the most severe form of acute disseminated encephalomyelitis (ADEM) and is characterized by an acute rapidly progressive fulminant inflammation of the white matter The neurological manifestations of dengue infection include encephalitis, meningoencephalitis, Guillain-Barre syndrome, myelitis, and myositis.1, 2, 3 There are a few reports of both hemorrhagic and ischemic stroke due to dengue hemorrhagic fever. We present a child with dengue vasculitis as the likely cause of ischemic stroke. Patient Descriptio Successful treatment of hemorrhagic bullous Henoch‐Schonlein purpura with intravenous immunoglobulins. Angela Mauro MD. Henoch‐Schonlein purpura (HSP) is the most common systemic vasculitis in childhood. There is no consensus about the management for isolated cutaneous manifestations in HSP. The 11‐year‐old child was treated. In children and teenagers, numbers are closer to 55% ischemic and 45% hemorrhagic. When people talk about stroke, they usually mean ischemic stroke because it is much more common. Ischemic stroke occurs when a blood vessel is blocked preventing blood flow to brain tissue causing death of brain cells

Hemorrhagic Vasculitis in Children and Adults: Causes

60 children with hemorrhagic vasculitis were examined in order to detect ultrasound and biochemical markers of endothelial dysfunction, depending on the degree of acti­vity and the form. Serum monocyte chemoattractant protein 1 (MCP-1) concentration was determined using enzyme-linked immunoassay, the content of nitric oxide by its stable. A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of a stroke may include an inability to move or feel on one side of the body, problems understanding or speaking.

Environmental causes: carbon monoxide poisoning, infection, medication, trauma, vasculitis, and dissection. Congenital causes: arteriovenous malformation, aneurysm, Moyamoya syndrome, and other cerebrovascular anomalies. Learn how Children's Hospital's Brain Care Institute treats children and infants with stroke. Learn more about Child Neurology The first form is an arthritis-dermatitis syndrome consisting of tenosynovitis, dermatitis, and polyarthralgias without purulent arthritis. 2 Acute illness is characterized by fever, chills, and. MRI of Cerebral Microhemorrhages. 1 Both authors: Department of Diagnostic Imaging, Brown Medical School, Rhode Island Hospital, 593 Eddy St., Providence, RI 02903. OBJECTIVE. The purpose of this pictorial essay is to discuss the differential diagnosis of cerebral microhemorrhages on T2 * -weighted gradient-echo MRI

[Clinical features of hemorrhagic vasculitis in children]

COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: Imaging Features. From the Department of Radiology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202. Address correspondence to B.G. (e-mail: brentg@rad.hfh.edu ). Since its introduction to the human population in December 2019, the coronavirus disease 2019 (COVID. categories include systemic vasculitis, hemoglobinopathies such as sickle cell disease, disorders of coagulation, and metabolic disorders. Approximately 30% of children have no identifiable risk factor present at stroke presentation. (1,12,14) However, children at risk often have multiple etiologies related to AIS. (1,12,15) Se Cutaneous vasculitis is a group of disorders in which there are inflamed blood vessels in the skin. These may include capillaries, venules, arterioles and lymphatics. Cutaneous vasculitis has several different causes. There are a wide variety of clinical presentations. It is associated with systemic vasculitis in a minority of patients West Nile virus (WNV) is a neurotropic flavivirus and the leading cause of mosquito-borne diseases in North America. In approximately 20% of cases, infection leads to a self-limited febrile illness and, in less than 1%, to a neuroinvasive disease often manifesting as meningoencephalitis with or without acute flaccid paralysis.1 Herein, we report the first case of WNV-associated CNS vasculitis.

[The clinical characteristics of hemorrhagic vasculitis in

Structural abnormalities of the cerebral arteries themselves, known as cerebral arteriopathies, can also cause AIS. Examples include cerebral vasculitis, Ehlers-Danlos syndrome and moyamoya disease. Hemorrhagic stroke. Rather than ischemia, or obstruction of blood flow, some strokes occur due to bleeding, or hemorrhage, within the brain IgA vasculitis is the most common vasculitis for children; it is usually seen in children between 3 and 10 years old (the age peak is 5-7 years) and very rarely in adults [3, 4]. The annual incidence varies greatly, from 13 to 20/100,000 for children to 0.8-1.8/100,000 for adults [6, 7, 8]

Hemorrhagic vasculitis - online presentation

Hemorrhagic cystitis is defined by lower urinary tract symptoms that include hematuria and irritative voiding symptoms. It results from damage to the bladder's transitional epithelium and blood vessels by toxins, pathogens, radiation, drugs, or disease. Infectious causes of hemorrhagic cystitis include bacteria and viruses PEARLS. The main clinical challenge in the management of acute stroke is the identification of rare but treatable causes. Ischemic and hemorrhagic stroke are well-known complications of CNS infection; cerebral vasculopathy related to herpes simplex virus 2 (HSV-2) presenting as brain hemorrhage has so far not been described in the literatur Henoch-Schönlein purpura (HSP), also known as IgA vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children.In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain.With kidney involvement, there may be a loss of small amounts of blood and. INTRODUCTION. While more common in older adults, stroke also occurs in neonates, infants, children, and young adults, resulting in significant morbidity and mortality. An overview of the presentation, evaluation, and diagnosis of arterial ischemic stroke in children one month of age or older is provided here. Other aspects of ischemic stroke in. Systemic vasculitis is an inclusive term applied to a group of disorders that cause inflammation in blood vessel walls with resultant ischemic tissue damage. Vasculitis syndromes are conveniently classified on the basis of the size of vessels typically involved, as shown in Table 55-7. Most are of unknown etiology

Viral hemorrhagic fevers are spread by contact with infected animals or insects. The viruses that cause viral hemorrhagic fevers live in a variety of animal and insect hosts. Most commonly the hosts include mosquitoes, ticks, rodents or bats. Some viral hemorrhagic fevers can also be spread from person to person. How is it transmitted Kawasaki disease Common in children with nonspecific subdural effusions, cerebral infarctions, atro-phy, or a reversible hyperintense lesion in the splenium of the corpus callosum IgA vasculitis Common in children 4-7 years old with hypertensive encephalopathy but with focal ischemic or hemorrhagic lesion 2. History. Purpura was the first manifestation of vasculitis in vessels smaller than arteries. In 1808, Willan clearly distinguished purpura caused by infections from non-infectious purpura [].Over the next century, Henoch and his teacher, Schönlein, described a broad spectrum of signs and symptoms that were associated with purpura, and with small vessel vasculitis, including arthritis.

culitis, resulting in profound vision loss in both eyes. A second case of hemorrhagic occlusive retinal vasculitis previously reported from our institution is summarized. That case was characterized by a far milder course, with rapid resolution of vision loss. The 2 cases illustrate the broad range of toxicity potentially associated with intracameral vancomycin, suggest that bilateral. Leukocytoclastic vasculitis (LCV) is mediated by immune complex formation and deposition in the vascular basement membrane zone, with subsequent activation of complement and influx of neutrophils. The inflammatory process and subsequent destruction of vessels result in hemorrhagic papules and nodules referred to as palpable purpura We characterized the complete genome of a novel dog circovirus (DogCV) from the liver of a dog with severe hemorrhagic gastroenteritis, vasculitis, and granulomatous lymphadenitis. DogCV was detected by PCR in fecal samples from 19/168 (11.3%) dogs with diarrhea and 14/204 (6.9%) healthy dogs and in blood from 19/409 (3.3%) of dogs with. Final visual acuity was 20/200 or worse in patients who developed hemorrhagic occlusive retinal vasculitis, probably as a hypersensitivity reaction to the antibiotic, said Andre Witkin, MD, from. Introduction. The term vasculitis includes a group of entities in which the common characteristic is inflammation of the walls of blood vessels ().Primary vasculitis is of unknown origin. Secondary vasculitis could be related to infection, malignancy, connective tissue disease, exposure to drugs, or environmental exposure ().The 1994 Chapel Hill Consensus Conference criteria classified.

(PDF) Vascular-Rheological Properties of Blood inBiomedical Science Med01501 &gt; Dr

Various inflammatory responses can occur after scabies infection, among which vasculitis is a rare form of reaction. Elwood et al 1 examined 25 biopsies of scabies infection, and leukocytoclastic vasculitis was only observed in one case (4%). To date, only several cases of scabietic vasculitis have been reported. 1-6 Some cases presented with purpuric lesions, 2,4,6 while others not, and. Background Acute hemorrhagic edema of infancy (AHEI) is a benign and self‐limiting disease that usually resolves completely without sequelae and without the need for active therapy. Most consider AHEI to be a separate entity from Henoch-Schonlein purpura (HSP), but others believe that they are different clinical presentations of the same disease Stroke in Children. A stroke is a brain injury caused by the interruption of blood flow to part of the brain. Stroke can be caused by a blocked blood vessel (ischemic stroke) or by bleeding in the brain (hemorrhagic stroke). The brain needs a constant supply of oxygen, which is carried by the blood. When blood flow stops, brain cells start to die Wegener's Granulomatosis Definition Wegener's granulomatosis is a very rare disease that affects many different organs and systems of the body. It mainly attacks the respiratory system (sinuses, nose, windpipe, and the lungs) and the kidneys. One of the main features of the disease is an inflammation of the blood vessels (vasculitis). The inflammation. Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease and Osler-Weber-Rendu syndrome, is a rare autosomal dominant genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver, and brain.. It may lead to nosebleeds, acute and chronic digestive tract bleeding, and various. BACKGROUND: Acute hemorrhagic edema of infancy (AHEI) is a rare leukocytoclastic vasculitis of the small vessels occurring at a young age and considered as a benign self-limited disease. Due to its low prevalence, there are limited data on the presentation and complications of this disease. METHODS: All computerized files of children who were.